Synvisc One Injection

synvisc one

What Is a Synvisc One Injection?

Synvisc One is a knee injection used as part of viscosupplementation. In simpler terms, it is meant to add more cushioning and lubrication inside the knee joint when the natural joint fluid is no longer doing that job well.

A healthy knee has fluid inside it that helps the joint move smoothly and absorb some of the pressure from walking, standing, and other daily movements. With osteoarthritis, that fluid can become less effective. Synvisc One improves how the joint moves by helping it glide more easily and better handle stress.

It does not rebuild the joint or “fix” worn cartilage. Instead, it works by improving the inside of the knee so movement may feel more comfortable.

Synvisc One Ingredients

Synvisc-One is made with a gel-like material called hylan G-F 20. This is a form of hyaluronan, a substance that healthy joints naturally use for cushioning and smooth movement.

It also includes a medical-grade liquid solution that helps hold everything together and keeps the Synvisc One injection stable. That solution contains salt, phosphate ingredients, and sterile water. These parts are not the main “active” part of the treatment. But they help create the right fluid environment for the gel component.

synvisc one injection
synvisc-one

When Synvisc-One Is Recommended

Synvisc-One is usually recommended for people with knee osteoarthritis who are still dealing with pain after trying more basic options first. That may include exercise, weight management, changes in activity, and over-the-counter pain medicine.

It’s often considered when knee pain is still limiting daily life even after more conservative care hasn’t helped enough. The goal is to give the knee more support inside the joint when simple measures are no longer doing the job.

Conditions We Treat in Chicago

synvisc one inj

What to Expect After a Synvisc-One Injection

After a Synvisc One injection, most people go home the same day. It’s usually a good idea to take it easy for about 48 hours and avoid heavy activity, high-impact exercise, or long periods of heavy weight-bearing. That means no jogging, tennis, or similar activities right away.

Knee pain relief does not happen the same way for everyone. Sometimes they happen pretty quickly, within a day or two, but sometimes it may take a week or more. If your knee pain returns later after the Synvisc-One injection, we can reevaluate and discuss the next step.

synvisc one injections

Synvisc-One Pros and Cons

Pros

Cons

synvisc one side effects

Possible Synvisc One Side Effects

Most Synvisc One injection side effects are described as mild and temporary, but patients should report anything unusual to their doctor:

  • Pain in or around the knee.
  • Swelling in or around the knee.
  • Warmth or heat in the knee area.
  • Redness around the knee.
  • Fluid buildup in or around the knee (joint effusion).
  • Pain or soreness at the injection site.
  • Joint stiffness or trouble walking normally for a short time.
  • Allergic reactions are possible, and in rare cases, they can be serious.
Get a personalized solution
for your pain needs

Choose Painless Medical Practice for a Synvisc One Injection in Chicago, IL

At Painless Medical Practice in Chicago, IL, we make Synvisc-One treatment simple and personal. Before administering the injection, we make sure it is actually appropriate for your knee and your situation. Our clinic is led by Jaroslav Tymouch, MD, Founder of Painless Medical Practice, so an experienced physician supervises your care.

We don’t use generic approaches. We review your case and consider if this option is a good match for you. We also respect your time and focus on care that is clear, practical, and medically appropriate, with as few sessions as reasonably possible.

If you’re looking for trusted pain management in Chicago, IL, schedule an appointment with our team to find out whether Synvisc-One is the right choice for managing your knee pain.

synvisc-one injection

Our Insurance Partners

We accept most of commercial insurances

FAQs About Synvisc One Injection in Chicago

What Is Synvisc One?

Synvisc-One is a knee injection used to add cushioning and lubrication inside the joint. It helps improve movement and reduce discomfort in people with osteoarthritis.

How Does Synvisc One Work?

Synvisc One injection works by improving the quality of joint fluid, helping the knee move more smoothly and absorb pressure better during daily activities.

What Are the Side Effects of Synvisc One?

Common side effects include temporary pain, swelling, warmth, redness, or fluid buildup in the knee. In rare cases, allergic reactions may occur.

How Long Does Synvisc One Take to Work?

Relief may begin within a few days, but for some people it can take a week or more to notice improvement.

What Is Synvisc One Made Of?

Synvisc-One is made of hylan G-F 20, a gel-like form of hyaluronan, along with a sterile solution that includes water, salts, and phosphate compounds to support the injection.

What People Say About Synvisc-One Injection

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4.8
Based on 32 reviews
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Rina Vidri profile picture
Rina Vidri
19:53 06 Dec 25
I recently visited Dr Tymouch, and I couldn’t be more impressed with the experience. From the start to the finish, the process was smooth and stress free. The doctor took time to explain the procedure clearly, answered all my questions, and made sure I felt comfortable throughout.
If you are looking for a knowledgeable, compassionate and highly skilled professional, I highly recommend Dr Tymouch. His expertise truly stand out!
Chris Stavrou profile picture
Chris Stavrou
22:40 13 Nov 25
Dr. Tymouch is simply the best! Cured my chronic plantar fasciitis in a month with a combo of laser, ultrasound, and a shot! Office is clean, no wait, every one is sooo nice! Highly recommend!
Esteban De chicago profile picture
Esteban De chicago
20:38 13 Nov 25
Had a horrible knee problem, came to the clinic and The Dr did a wonderful job. No more pain. The Dr. was recommended by some friends. One thing is for sure. He knows what he is doing for sure. Esteban. Thank you Doc.
Vets Kolom profile picture
Vets Kolom
16:16 01 Nov 25
I recommended this clinic for everyone. I feel much excellent after I saw Dr. Tymouch and had some physical therapy.
Olga Volochiy profile picture
Olga Volochiy
20:49 20 Jul 25
Dr. Tymouch, thank you for your help. Thanks to you, I got rid of the pain. I recommend this wonderful doctor to everyone
Iryna Lemeha profile picture
Iryna Lemeha
04:32 20 Jul 25
I came to Dr. Yaroslav Tymouch with heavy knee pain just days before an upcoming vacation. A friend recommended him—and I’m so glad they did! From the moment I walked into Painless Medical Practice, the atmosphere was welcoming, calm, and professional.
Dr. Tymouch took the time to carefully explain everything, answer my questions, and made me feel completely at ease throughout the entire visit. He treated my knee pain with injections, and the results were truly amazing and fast. I happy that I will be able to enjoy my vacation without discomfort. I’m so grateful for his care and highly recommend Dr. Tymouch to anyone in need of expert, compassionate treatment.
Roman profile picture
Roman
20:44 31 May 25
My grandma Halyna Zacharkiw just had an appointment here. Dr Jaroslav Tymouch was a professional, she had nothing but nice things to say about him.
Natali Kulynych (NK) profile picture
Natali Kulynych (NK)
00:14 23 May 25
Great Doctor!! Very kind and really helped me feel better. I’m so thankful and truly recommend him to everyone🙏
Andrii Golovatskyi profile picture
Andrii Golovatskyi
21:02 20 May 25
Great service and excellent quality of work by Dr. Yaroslav Tymouch.
Olha Stetsko profile picture
Olha Stetsko
21:31 01 May 25
I really like this clinic. The staff is incredibly knowleageable and welconig. Highly recommend for anyone lookingfor quality care.
Olga Mago profile picture
Olga Mago
15:18 26 Mar 25
I recently visited Dr. Jaroslav Tymouch’s office in Ukrainian village, and I had a very positive experience. He is an excellent pain doctor who truly listens to his patients. He takes the time to understand concerns and provides clear explanations, which is very helpful. I appreciate his professionalism and compassionate approach to care. I highly recommend Dr. Tymouch to anyone in need of a knowledgeable and attentive pain specialist.
Dana Hirt profile picture
Dana Hirt
02:56 19 Mar 25
I am finally getting relief after being recommended to Dr.Tymouch! He has taken a multi-pronged approach to my on-going hip and leg pain. He is attentive and thoughtful and Victoria is professional and caring. Worth making an appointment if you want to explore different modalities and get results.
oleg muzyka profile picture
oleg muzyka
23:07 06 Mar 25
It was meeting with wery professional doctor. Thanks for your help!
Iryna Amelchenko profile picture
Iryna Amelchenko
19:54 25 Feb 25
Igor Shpak profile picture
Igor Shpak
00:45 10 Feb 25
Thank you for your professionalism! Your treatment inspires faith in recovery even in very difficult cases. I recommend everyone to contact Mr. Tymosh and not to delay the visit to those who have joint problems. Friendly staff, everything is at a high level. Thank you very much!
Volodymyr Kravchuk profile picture
Volodymyr Kravchuk
16:42 08 Feb 25
I am very satisfied with the service of Dr. Tymosh
Daryna Khodanovych profile picture
Daryna Khodanovych
14:13 29 Jan 25
Painless Medical Practice truly lives up to its name!
The team is professional, compassionate, and highly skilled at managing different types of pain.
Велике дякую Ярославу Тимошу за лікування моїх батьків, вони вже постійні пацієнти цього лікара, завжди назначить правильне лікування, хто має проблеми зі здоров’ям, а саме ті хвороби що лікує пан Тимош , звертайтеся, не пожалуєте. Мої батьки усім своїм знайомим рекомендують цього лікара!
Arturo Avila profile picture
Arturo Avila
17:58 20 Sep 23
My father ( 97 years old) recently had his pain injections with Dr. Tymouch. I worked in health care for 38 years along side many physicians and speaking from experience I can honestly say he delivered exceptional care and great bedside manners. If I personally ever need pain injections he will definitely be the doctor I go to.
Jonathan Ortega profile picture
Jonathan Ortega
19:33 02 Apr 22
Amazing! I was having many issues with providers due to a special insurance case. I was turned away 5+ times even though I would have coverage and Dr. Tymouch was the first doctor I spoke with that actually listened to me and gave me care. The staff is well trained and very efficient, so grateful for the life changing work they do!
Viktoria Kontseva profile picture
Viktoria Kontseva
02:45 29 Aug 20
Dr. Tymouch is an incredible doctor! He helped me relieve my knee pain with injections and it worked wonders! I highly recommend coming to him with any pain issues!
Alexander Gordon profile picture
Alexander Gordon
22:15 21 Aug 20
I have been in pain for many years and Dr. Tymouch has been God sent. Thank you.